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Ozone Hard Shampoo
€17,10
€19,00
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It is a line of shampoo therapy indicated for the hygienic treatment of skin with dermatitis, atopic tendency, with inflammatory dermatoses, food allergies and/or desquamative conditions with primary lesions: erythema, papules, pustules and/or plaques, as well as hyperkeratosis, lichenification, hyperpigmentation and/or seborrhea.
Hard shampoo is especially formulated for severe stages or outbreaks. It is formulated with natural plant extracts especially indicated for sensitive skin, as well as argan oil and xylitylglucoside, providing a moisturizing action on the skin, and lipoamino acids, present in cellular structures such as Capryloyl Glycine.
Ozone Hard Shampoo
€17,10
€17,10
Validated clinical study
Effectivenessprovenby veterinary dermatologists
PSH's Ozone line has undergone an independent clinical study on pyoderma and canine atopic dermatitis, published in the specialized journal Clindervet No. 40 (June 2025).
87%
Average reduction in injuries in CADESI-4
After 45 days of treatment
50%
Of the patients with complete remission
Symptoms completely resolved
90%+
Reduction in just 9 days
Acute urticarial CAD (Yorkshire)
Study Objective
What was measured?
The study evaluated the reduction of skin lesions—mainly pyoderma and canine atopic dermatitis (CAD)—treated only with PSH Ozone line shampoo therapy, without systemic antibiotic support.
Canine atopic dermatitis affects 15-20% of the canine population, with lesions in interdigital, auricular, axillary, inguinal, and facial areas. The most frequent bacterial pathogen is Staphylococcus pseudointermedius.
Methodology
How it was performed
N = 15 dogs with pyoderma or CAD diagnosis confirmed by a veterinary dermatologist.
45 days of follow-up with 4 veterinary visits (days 0, 15, 30, and 45) or until clinical cure.
Objective measurement using the CADESI-4 scale (erythema, lichenification, excoriations, alopecia) + review cytology.
Protocol: Shampoo therapy + Ozone Foam every 2-3 days during active flare-ups, gradually spacing out as symptoms improve.
Real case: 3-year-old Yorkshire Terrier — Acute urticarial ACD
CADESI-4 Evolution by Parameter
| CADESI-4 parameter | Day 0 | Day 3 | Day 6 | Day 9 |
|---|---|---|---|---|
| Erythema | 3 | 2 | 1 | 0 |
| Lichenification | 2 | 1 | 0 | 0 |
| Abrasions | 3 | 2 | 1 | 0 |
| Alopecia | 3 | 2 | 1 | 1 |
| TOTAL | 11 | 7 | 3 | 1 |
91% reduction in total CADESI-4 in just 9 days. Study published in Clindervet No. 40, June 2025.
CADESI-4 score evolution (mean 15 cases)
Veterinary visits
Visit 1 · Day 0
11
Initial score. Active lesions.
Visit 2 · Day 15
6.2
44% reduction. Visible improvement.
Visit 3 · Day 30
3.1
72% reduction. Skin recovering.
Visit 4 · Day 45
1.4
–87% on average. 50% asymptomatic.
The treatment protocol
Step 1A
Ozone Soft Shampoo
For mild dermatoses
Apply with massage to the entire affected area. Remove with water. Use every 2-3 days during active outbreaks.
Step 1B
Ozone Hard Shampoo
For severe dermatoses
Higher concentration of active ingredients for cases with erythema, pustules, or secretions. Same application as Soft.
Step 2
Ozone Sweet Conditioner
Post-bath in severe dermatoses
Apply after shampooing. Leave hair completely dry and free of moisture after conditioning.
3
Combined assets
Dermapet Pure®
Hexylene Glycol
Capryloyl Glycine
Xylitylglucoside
They repair the altered skin barrier, control excess oil, and inhibit 5α-Reductase and Malassezia furfur.
5
Natural extracts
100% plant-based
Aloe Vera
Argan Oil
Vegetable Glycerin
Lemon Balm
Chamomile
¹ Efficacy study carried out by a specialist veterinarian on 15 cases of dogs with CAD or pyoderma treated with the PSH Ozone line. ² Evolution of an acute outbreak of urticarial dermatitis secondary to CAD in a 3-year-old Yorkshire. Study published in Clindervet nº40, June 2025, by Drs. José Ignacio Gutiérrez Contreras and Verónica García de la Peña. More information at pshcosmetics.com.
