Dermatological Ozonotherapy PSH Treatment

March 15, 2025

Tratamiento dermatológico de Ozonoterapia PSH

Efficacy Study of the PSH Ozone Range in Canine Pyoderma and Atopic Dermatitis (CAD)

Canine atopic dermatitis (CAD) is a genetically predisposed, inflammatory, and pruritic disease with characteristic clinical manifestations, with a prevalence of 15-20% in canines.

It is common to observe lesions located interdigitally, aurally (especially on the concave surface of the pinna and in the vertical canal of the external auditory meatus), on the abdomen, in the armpits, perineum, facial region (periocular, labial, skin folds), as well as generalized involvement, affecting several or all of the mentioned areas. An individualized manifestation for each breed, with specific patterns of extension, is also common.

Other types of lesions such as excoriations, lichenification, and hyperpigmentation (chronic presentation) can also be observed. The appearance of superficial or surface bacterial pyoderma and the presence of Malassezia spp dermatitis are common situations.

Both superficial and surface pyoderma often appear as secondary complications to underlying CAD, and are somewhat due to alterations in the skin barrier, a fundamental aspect in understanding the pathogenesis of Canine Atopic Dermatitis.

The most frequent bacterial population is the presence of Staphylococcus pseudointermedius spp, with areas of erythema, crusts, and in complicated forms, purulent secretions.

These lesions are usually concentrated in the folds of the skin, such as the armpits, groin, and ventral side of the neck, primarily causing intertrigo or pyoderma of the skin folds.

The success in managing these pathologies, after proper diagnosis, lies in combining treatment and control strategies.
Jose Ignacio (Veterinary Expert)

EFFICACY STUDY

Objective

Measure the reduction of lesions, mainly due to pyoderma and CAD, treated solely with PSH's Ozone line shampoo therapy.

Methodology

Topical treatment using a shampoo therapy + foam protocol in 15 cases with pyoderma or CAD lesions, until clinical cure or fourth veterinary visit (45 days), through a protocol and negative cytology review.

N=15 dogs
Measurement in CADESI-4

OZONE PSH TREATMENT PROTOCOL

Shampoo Therapy

Ozone Soft and Hard Shampoo

Apply the shampoo (Soft for mild problems, Hard for severe ones) with a massage over the entire area to be treated, and rinse off the product.

Ozone SWEET Conditioner

Apply the Sweet conditioner after using the shampoo. We recommend that the hair be dry and free of moisture after washing.

Every 2 or 3 days in case of an outbreak; once improvement is observed, the time between washes is spaced out.

Pre & Post Shampoo Therapy

Ozone Foam

Apply the foam to the localized surface until completely absorbed. Use between baths, before and after. Daily.

RESULTS

An 87% average reduction in CADESI-4 lesions was observed at the fourth specialist veterinary visit (45 DAYS).

In half of the patients, symptoms completely resolved.

CAD case in a 3-year-old Yorkshire

Evolution of acute urticarial dermatitis outbreak secondary to CAD in a 3-year-old Yorkshire in CADESI-4*

In just 9 days, a reduction of more than 90%**

*Efficacy study conducted by a veterinarian, on 15 cases of dogs with CAD or pyoderma treated with PSH Ozone line.
**Evolution of acute urticarial dermatitis outbreak secondary to CAD in a 3-year-old Yorkshire

PSH OZONE LINE

Shampoo therapy line, with Dermapet Pure, indicated for the hygienic treatment of skin with dermatitis, atopic tendency, with inflammatory dermatoses, food allergies and/or desquamative conditions with primary lesions: erythema, papules, pustules and/or plaques, as well as hyperkeratosis, lichenification, hyperpigmentation and/or seborrhea.